Fernandes converted two penalties before completing a hat trick in the 87th minute to set up a last-eight matchup with Lyon.
Conor Benn and Chris Eubank Jr are set to square off at the Tottenham Hotspur Stadium in London on April 26 and are engaged in a fiery build-up to the contest.
Bruno Fernandes’ hat-trick helped United beat Real Sociedad 4-1, while Friday will see new England boss Thomas Tuchel name his first squad.