Complementary biochemical and structural findings reveal molecular principles underlying substrate selectivity by a model hyaluronan synthase.

Researchers at the University of Waterloo have produced experimental evidence that quantum-level effects can alter the ...

In practical applications, nothing determines the success of a biocatalysis project more than the precise match between the enzyme and the substrate. Many industrial projects encounter issues such as ...

All complex biological systems—like the DNA, RNA and proteins constantly being copied and built within our cells—are prone to errors. That means as life evolved to be more elaborate, it also had to ...

The controversial process of enhanced enzyme diffusion could enable living systems to resist local equilibrium ...

University of North Carolina at Chapel Hill postdoctoral researcher Samruddhi Jewlikar applies protein engineering and ...

Understanding the fundamental parameters of enzyme kinetics can feel like learning a new language, especially when the terms look nearly identical. If you’ve ever found yourself staring at a Michaelis ...

DOMEK is a multi-step pipeline which leverages mRNA display-derived next-generation sequencing data to derive kinetic information about substrates of post-translational modification enzymes.

In a concerning development for infectious disease management, researchers have identified the emergence of ceftazidime-avibactam resistance in Klebsiella pneumoniae during the course of therapy, ...

Engineered enzymes with enhanced or novel functions are specific catalysts with wide-ranging applications in industry and medicine. Here, we introduce droplet array microfluidic enzyme kinetics ...