Janelia researchers have uncovered a novel way that two of the structures inside cells—the endoplasmic reticulum (ER) and ...
When human cells lack oxygen, they must react. Without oxygen, the metabolism can hardly generate energy, and many vital ...
When improperly folded proteins build up in the endoplasmic reticulum (ER), cells become stressed and conditions such as type 2 diabetes, neurodegenerative disorders, and cancers can develop. In a ...
About one-fourth of recurrent estrogen receptor-positive (ER+) breast cancers lose ER expression, which renders them resistant to endocrine therapy and able to grow uncontrolled. A team of researchers ...
De novo cholesterol biosynthesis is a key metabolic vulnerability in rhabdomyosarcoma. Its inhibition halts cell ...
According to "Global Cancer Statistics- 2022", colorectal cancer (CRC) ranks third in incidence and second in cancer-related mortality. Given that ...
The current pandemic of coronavirus disease 2019 (COVID-19) has spurred intense interest into the mechanisms of cell damage and tissue death following infection by the severe acute respiratory ...
Innovative fiber optic–based approach of HER2 expression quantitative assessment using inPROBE technology. Real-world data comparison of time to next treatment for patients with HER2 positive ...
Proteins are often called the building blocks of cells, but even those building blocks need to be built. One of the most ...
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