The cell's endoplasmic reticulum (ER) plays a central role in protein synthesis, folding, and calcium (Ca²⁺) storage. When damaged, ER-phagy (self-eating) removes affected ER regions via ...
The body's cells change their shape to close gaps such as wounds – with part of the cell flexing depending on the curve of the gap and the organization of cell-internal structures, a new study reveals ...
Cancer drugs are often designed to block specific molecular targets, but what happens after they enter a cell is not always ...
The endoplasmic reticulum (ER) is a major organelle responsible for protein folding and trafficking. Protein folding stress in the ER can lead to the accumulation of unfolded or misfolded proteins, ...
When improperly folded proteins build up in the endoplasmic reticulum (ER), cells become stressed and conditions such as type 2 diabetes, neurodegenerative disorders, and cancers can develop. In a ...
Caption The ER (in yellow) almost covers the entire expanse of a cell. (left) Tube-like ER structure at the cell periphery near a convex shaped gap boundary; (right) Flattened sheet-like ER structure ...
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