Inside cells, there exists an extensive system of canals known as the endoplasmic reticulum (ER), which consists of ...

University of Western Australia research reveals how cells convert physical exercise forces into energy production responses.

He thinks beta cell death in type 2 diabetes may occur when the cells’ protein-folding factories become overtaxed from having to prepare so much insulin for export. ER Stress and Beta Cell Death All ...

The peripheral endoplasmic reticulum (ER) forms a continuous, dynamic network of tubules that plays an important role in protein transport and quality control, cellular signaling, and stress response.

The ER is the cells main “shipping port” that packages proteins and lipids, checks their quality, and facilitates their transport within the cell. For these vital processes, energy in the form of ATP, ...

About one-fourth of recurrent estrogen receptor-positive (ER+) breast cancers lose ER expression, which renders them resistant to endocrine therapy and able to grow uncontrolled. A team of researchers ...

“Working with a mouse model of human ER+ breast cancer, we were surprised to find that overexpressing 14-3-3τ in these tumors led to all the cancer cells becoming ER-negative (ER-),” said Lin ...