Williams isn’t the only 49er destined for the Hall of Fame who could have ended up in Los Angeles. In 2022, San Francisco general manager John Lynch detailed how he won a “a 49ers-Rams tug-of-war” in getting star running back Christian McCaffrey from Carolina.

The 49ers have a huge divisional showdown Sunday against the Rams, but they may not have Ricky Pearsall or Brandon Aiyuk back for the Week 10 game at Levi's Stadium.

Riding a three-game win streak, the Rams will look to keep that momentum going approaching a Week 10 showdown against divisional rival San Francisco at Levi's Stadium. Kickoff against the 49ers in Santa Clara is scheduled for 1:25 p.m. pacific time on FOX.

Week 10 of the NFL season is already upon us, and the challenge of setting lineups and finding an edge in fantasy football only becomes greater than the week before. While talent and matchups always matter,

Get the full 49ers Week 10 practice and media schedule ahead of their matchup vs. the Rams, including press conferences and practice times.

These coaches are friends who joined the division at the same time, are considered offensive geniuses and have had successful tenures as coaches of their respective teams. When they meet on NFL Thursday Night Football, McVay’s Rams are in much better shape when it comes to team health and availability.

The San Francisco 49ers play the Los Angeles Rams this week, and 49ers HC Kyle Shanahan said Brock Purdy will start once he’s healthy again. Nick Wright, Chris Broussard, Kevin Wildes, and Greg Jennings ask if this is the right decision despite Mac Jones’ performances,

The 49ers’ lone move was sending a sixth-round pick to New England on Oct. 28 for end/tackle Keion White, who was a second-round pick in 2024 but not considered a fit with the defensive scheme brought in by coach Mike Vrabel. The 49ers also got back a seventh-round pick in the deal.

The Los Angeles Rams are optimistic that star wide receiver Puka Nacua can return for a Week 10 showdown versus the San Francisco 49ers.