The Week 15 NFL DFS main slate is one of the largest of the season with 13 games kicking during the afternoon windows. Though the NFL DFS player pool has increased, so has the size of many injury lists this time of year.

Check out our expert predictions and best bets for Bears vs. Browns in NFL Week 15. Is an NFL record about to be broken?

The Arizona Cardinals and Houston Texans clash on Sunday at 1 p.m. ET in Houston. The Texans are heavy favorites. They have the No. 1 defense in the league and have won five games in a row.

The Chicago Bears will try to regain their footing Sunday when they host the floundering Cleveland Browns in NFL Week 15. The Bears (9-4) saw their five-game win streak snapped with a loss to the rival Green Bay Packers last week,

Is De'Von Achane about to run circles around another defense? Which Rams receiver will catch four touchdown passes from Matthew Stafford? Our analysts provide bold predictions for Week 15 of the 2025 NFL season.