Diabetes mellitus affects more than 500 million people worldwide, and both Type 1 (T1D) and Type 2 (T2D) forms converge on a common endpoint: the loss or ...

A new Cell study suggests that T cell exhaustion in tumors is driven in part by failed proteostasis, causing damaged and misfolded proteins to accumulate inside tumor-infiltrating lymphocytes. Restori ...

B lymphocytes exhibit dual roles in tumorigenesis, acting as both allies and adversaries in the tumor microenvironment (TME). Their anti-tumor functions include recognizing tumor-associated antigens, ...

Until now, doctors knew hepatic stellate cells mainly as drivers of liver fibrosis. The actual functions of this cell type have hardly been studied to date. Researchers have now determined that ...

Dr. Zhao said several of RS3's proteins are involved in placing or removing phosphate groups from other proteins—a regulatory function that he and his colleagues suspect plays a part in coordinating ...

In a new study published in Science titled, “Mitochondrial metabolism and signaling direct dendritic cell function in antitumor immunity,” researchers from St. Jude Children’s Research Hospital have ...

A patent awarded to an elite-funded biomedical research institution details technology described as enabling the 'remote ...