In certain contexts, the Notch receptor may participate in “reverse signaling,” influencing neighboring cells directly.

The study, “Integration of phospho-signaling and transcriptomics in single cells reveals distinct Th17 cell fates,” was published in Cell Reports. In the study, first author Seth Fortmann, M.D., Ph.D.

T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on exquisitely timed molecular signals. Now researchers have captured one of the ...

[button url="http://chem.colorado.edu/" color="blue"]Department of Chemistry and Biochemistry[/button] [button url="www.colorado.edu" color="blue"]University of ...

Squeeze a cell once and it barely flinches. Squeeze it again and again in short bursts, and something changes: a protein called YAP migrates into the nucleus and flips on genes that drive tissue ...