Polyclonal antisera against rat visceral yolk sac (VYS) produces severe congenital malformations when injected into pregnant rats on the 9th day of gestation. To define and characterize the ...

May 18, 2004 — Phenobarbital is significantly teratogenic, according to the results of a six-year registry of antiepileptic drugs (AEDs) published in the May issue of the Archives of Neurology.

The researchers tallied 7 total congenital malformations out of 120 exposures, including 2 cardiac valvular defects, 1 kidney malformation, and 2 bony malformative disorders. CHICAGO — Bisphosphonate ...

DURING a study of the teratogenic effects of heavy metals on mammalian embryos, we have been able to produce severe developmental malformations in golden hamster embryos by the intravenous injection ...

In a recent study published in JAMA Network Open, researchers evaluated the risk of congenital malformations following antibiotic treatment for urinary tract infection (UTI) during the first trimester ...

Nearly 50 years ago, an increasing number of babies worldwide were born with deformities and missing limbs. The babies had fallen victim to the teratogenic effects of thalidomide, a drug commonly ...

Thalidomide is a white powder sparingly soluble in water, and for that reason it was administered to rabbits as a suspension in physiologic saline solution containing 0.5 per cent ...

mRNA COVID-19 vaccines in early pregnancy do not increase the risk of major congenital malformations in infants. The study used data from the Mother-Child EPI-MERES Register, covering over 99% of the ...