Medical Xpress

Subretinal adeno-associated virus T-cell inhibition: Exploring potential existence of anti-transgene immune responses

A new study shows that subretinal adeno-associated virus 8 (AAV8) injections cause proinflammatory T-cell immune response against the transgene product. According to the study, published in the ...
Ophthalmology Times

Phase 3 data support OTX-TKI’s durability in wet AMD: 1 injection, 1 year

A novel intravitreal axitinib hydrogel demonstrated durable disease control in patients with treatment-naive neovascular age-related macular degeneration (AMD), with superior maintenance of visual ...
Healio

PPV, subretinal tissue plasminogen activator injection effective for submacular hemorrhage

Please provide your email address to receive an email when new articles are posted on . Pars plana vitrectomy with subretinal tissue plasminogen activator injection led to significant vision ...
Healio

Expert shares tips for safe subretinal delivery of gene therapy

Please provide your email address to receive an email when new articles are posted on . FORT LAUDERDALE, Fla. — Best practices for safe subretinal delivery of gene therapy were presented at the Retina ...
Business Wire

Gyroscope Therapeutics Announces First Patient Received Investigational Gene Therapy GT005 Via Orbit Subretinal Delivery System in Ongoing Phase I/II FOCUS Trial

LONDON--(BUSINESS WIRE)--Gyroscope Therapeutics Limited, a clinical-stage retinal gene therapy company, today announced that the first surgery using its proprietary Orbit™ Subretinal Delivery System ...