Single-cell RNA sequencing (scRNA-seq) has emerged as a powerful tool to record and dissect gene expression of individual cells in tissues. Compared to bulk RNA-seq, where RNAs from all cells in a ...
Pooled genome editing combined with single-cell RNA sequencing—commonly known as Perturb-seq—has transformed the ability to interrogate genome function. However, whole-transcriptome single-cell RNA ...
Chimeric antigen receptor T cell (CAR-T) therapy is considered one of the landmark achievements of modern medicine. The therapy involves harvesting a patient’s own immune cells, genetically ...
A new single-cell technology is giving scientists their clearest view yet of immune cell behavior—capturing not just genetic intent, but real-time activity. By measuring RNA and proteins ...
As single-cell genomics experiments grow in size, so too does the need for sequencing. Several large projects have recently called on the relative newcomer to the NGS scene, Ultima Genomics, for their ...
A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...
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Microcompartment approach expands possibilities for studying viruses in the environment
A new method vastly improves on the existing approach for single-cell genetic sequencing, enabling scientists to read the genomes of individual cells and viral particles in the environment more ...
A new method vastly improves on the existing approach for single-cell genetic sequencing, enabling scientists to read the genomes of individual cells and viral particles in the environment more ...
A team from the Andalusian Center for Molecular Biology and Regenerative Medicine (CABIMER) has developed an innovative technique called PLAMseq (proximity-labeled affinity-purified mass spectrometry ...
A comprehensive multi-cancer study by researchers at The University of Texas MD Anderson Cancer Center has revealed that ...
In just a few decades, DNA sequencing technologies evolved from slow, manual processes to rapid, automated ones, making ...
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