DNA sequencing from bulk or clonal human tissues has shown that genetic mosaicism is common and contributes to both cancer and non-cancerous disorders. However, single-cell resolution is required to ...

Genetic information flows in one direction, from DNA to RNA to protein — this central dogma forms the foundation of molecular biology. With single-cell technology we can explore each step of this ...

Single-cell sequencing is useful for a number of applications. For example, it can reveal cellular heterogeneity inside complex tissues, such as tumors. It can also provide information about how ...

Single-cell RNA-seq (scRNA-seq) has spent the past decade maturing into a foundational technology. Over that time, the technology has both laid the foundation for building cell atlases and allowed ...

As single-cell genomics experiments grow in size, so too does the need for sequencing. Several large projects have recently called on the relative newcomer to the NGS scene, Ultima Genomics, for their ...

You don't want to miss this! To permanently access this eBook for free, fill out the short form below. Single-cell sequencing is a valuable tool for analyzing complex cellular populations, enabling ...

Hypertrophic scars (HS) are abnormal outcomes of wound healing, marked by excessive extracellular matrix (ECM) deposition and ...

A comprehensive multi-cancer study by researchers at The University of Texas MD Anderson Cancer Center has revealed that ...

Scientists at St. Jude Children's Research Hospital, the National Center for Genomic Analysis and the University of Adelaide have created a single-cell RNA analysis method that is 47 times cheaper and ...

In just a few decades, DNA sequencing technologies evolved from slow, manual processes to rapid, automated ones, making ...

A new study constructs the first 3D single-cell brain atlas of the lamprey, uncovering the 450-million-year-old molecular blueprint of vertebrates.