Choosing the proper sample size for an investigation is one of the crucial jobs required of a statistician. Regardless of whether the statistician is deciding the number of patients to select in a ...

For a desired power of detecting the association between a disease and several potential risk factors in case-control studies, Yang (1978, Biometrika 65, 635-640) and Halperin (1980, Biometrika 67, ...

Implementation of the Time-to-Event Continuous Reassessment Method Design in a Phase I Platform Trial Testing Novel Radiotherapy-Drug Combinations—CONCORDE BayeSize applies the concept of effect size ...

Individual prediction uncertainty is a key aspect of clinical prediction model performance; however, standard performance metrics do not capture it. Consequently, a model might offer sufficient ...

Hi, I hope this is the best forum for this question and that someone can enlighten me with a clear answer. I work in a head office of a bank. One of my responsibilities is Quality Checking the work of ...

Several criteria for Bayesian sample size determination have recently been proposed. Criteria based on highest posterior density (HPD) intervals from the exact posterior distribution in general lead ...