High-accuracy protein complex structure modeling based on sequence-derived structure complementarity
In living organisms, proteins perform key functions required for life activities by interacting to form complexes. Determining the protein complex structure is crucial for understanding and mastering ...
We first summarize the framework of the proposed TDFold. Then, we conduct comprehensive experiments on multiple popular protein datasets, including Orphan, Orphan25, CASP14, CASP15 and CASP16. Finally ...
With MassiveFold, scientists have unlocked AlphaFold's full potential, making high-confidence protein predictions faster and more accessible, fueling breakthroughs in biology and drug discovery. Brief ...
Proteins are the molecular workhorses of the human body. They perform a vast range of essential functions, from building ...
In 2020, news headlines repeated John Moult’s words at the end of a stunning competition: Artificial intelligence had “solved” a long-standing grand challenge in biology, protein structure prediction.
Proteins are the molecular workhorses of cells. To understand their functions, scientists soon realized that they had to figure out proteins’ shapes. But solving a protein structure is a challenging ...
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