Looking for a different twist on the Jaguars-Chiefs game? Watch Eli and Peyton Manning's ManningCast coverage.
Watching the Chiefs' goal-line offense with Heidi Gardner on the ManningCast, Peyton Manning hilariously reacted to Patrick Mahomes' pick-6.
Gardner, a Saturday Night Live alumnus with great comedic timing, chose JuJu Smith-Schuster, but in a cruel twist of irony, the ball did end up going his way, only for Devin Lloyd to pick it off ...