Researchers led by a team at Baylor College of Medicine have identified a novel neurodevelopmental disorder associated with mutations or deletions affecting a gene called PAX5. Their findings are ...

The research team’s scientific paper was published in the Journal of Clinical Investigation (JCI) and showed that 395 genes are differently expressed in the pancreatic islets in individuals with type ...

Walter and Eliza Hall Institute researchers have revealed how immune health is maintained by the exquisite organisation skills of a protein called Pax5 Walter and Eliza Hall Institute researchers have ...

The commitment of lymphoid cells to the B cell lineage and maintenance of a B cell phenotype require the transcription factor PAX5, which is expressed by B cells at all stages of differentiation, but ...

PAX5 regulates B-cell identity by controlling the activation of its genetic program, guiding B-cell progenitors through the maturation process. According to the research, this is an exceptionally ...

Oncology researchers have long believed the protein Pax5 is merely a “transcription factor,” meaning it helps cells transcribe vital genetic information. But scientists in Australia believe they’ve ...