Before testing new therapies in animals, researchers now have a more efficient starting point—lab-grown canine muscle cells ...
During development, biological tissues acquire their shape and organization by integrating internal and external cues, with mechanics playing a central role. Mechanical forces steer cell behavior and ...
The neuromuscular junction (NMJ) is essential for transmitting signals from motor neurons (MNs) to skeletal muscles (SKMs), and its dysfunction can lead to severe motor disorders. However, our ...
Harvard stem cell biologists have pioneered a groundbreaking 3D organoid culture method for generating large numbers of adult skeletal muscle satellite cells, also known as muscle stem cells, in vitro ...
A new research paper was published in Volume 18 of Aging-US on May 15, 2026, titled “Extracellular vesicles released by ...
Researchers typically create organoid models for other biological systems with pluripotent stem cells, but the Harvard team began with readily accessible myoblasts, which satellite cells differentiate ...
Space exploration activity has been increasing. In turn, researchers are more interested than ever in uncovering more about how space travel affects human health and the progression of disease.
The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...