MetroLoft founder Nathan Berman calls the Manhattan high-rise structural damage a "freak accident" limited to a 20-by-20-foot section of the building.

Two columns on the 21st floor of a building under construction in Manhattan buckled Tuesday morning, triggering a slate of street closures and a large emergency response, according to the FDNY. The FDNY said it got a call around 8 a.

The unstable building on East 42nd Street is now "safe and stable," according to the Department of Buildings commissioner.

The building on East 42nd Street, the former headquarters of Pfizer, was being converted to apartments. Several upper floors were sagging.

As officials continue to investigate the cause, experts say that if the conversion is to proceed, "extensive work" would need to be done to shore up the damage and evaluate the building's safety and integrity.

UPPER EAST SIDE, Manhattan (PIX11) — The NYC Department of Health has ordered “multiple” buildings on the Upper East Side of Manhattan to drain, clean and disinfect their rooftop cooling towers as the city investigates a cluster of Legionnaires’ Disease cases.

As of Wednesday morning, the only streets closed off around 235 E. 42nd St. is E. 42nd St and E. 43rd St. between Second and Third Avenues, city Department of Buildings Commissioner Ahmed Tigani said at a presser outside the building