Switching to the drug letrozole following 5 years of treatment with tamoxifen reduces the risk of hormone-dependent breast cancer recurrence, but not overall survival, among postmenopausal women, ...

The study by Regan and colleagues presents an update on efficacy outcomes in the Breast International Group (BIG) 1-98 study at 8.1 years median follow-up. BIG 1-98 is a randomized, phase 3, ...

Benefit From Exemestane As Extended Adjuvant Therapy After 5 Years of Adjuvant Tamoxifen: Intention-to-Treat Analysis of the National Surgical Adjuvant Breast and Bowel Project B-33 Trial This report ...

Prognostic Importance of MN1 Transcript Levels, and Biologic Insights From MN1-Associated Gene and MicroRNA Expression Signatures in Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and ...

In the long term, the aromatase inhibitor letrozole is more effective at preventing the return of breast cancer and significantly improves survival time compared with tamoxifen in postmenopausal women ...

Letrozole extends the benefits of tamoxifen. * THE QUESTION Tamoxifen is generally effective at preventing recurrent breast cancer, but taking this drug for more than five years has been found to ...

Share on Facebook. Opens in a new tab or window Share on Bluesky. Opens in a new tab or window Share on X. Opens in a new tab or window Share on LinkedIn. Opens in a new tab or window Five years of ...

Please provide your email address to receive an email when new articles are posted on . Use of an aromatase inhibitor instead of tamoxifen reduced the risk for breast cancer recurrence among ...

The Breast International Group (BIG) 1-98 study evaluated adjuvant endocrine therapy in postmenopausal women who had hormone receptor-positive early-stage breast cancer. The study participants were ...

CHICAGO (Reuters) - Taking the breast cancer pill Femara can significantly reduce the chances that a woman's cancer will return, even long after she has stopped taking the estrogen blocker tamoxifen, ...

Women now have another drug they can take to prevent breast cancer from returning after surgery to remove the tumor. The federal Food and Drug Administration on Wednesday approved a new use for Femara ...

OUR resident specialist and NHS GP, Dr Zoe Williams, shares her expert advice. Today, Dr Zoe helps a reader who is suffering horrendous hot flushes since their breast cancer diagnosis. Please provide ...