The Tampa Bay Buccaneers versus the Seattle Seahawks is a game to catch on a Week 5 NFL schedule that features plenty of competitive matchups. If you're seeking additional betting intel for Week 5 in the NFL, we've got you covered with odds for all the big games.

NFL byes will begin in Week 5, but 10 games will still be played Sunday. Here's a look at which ones will be available in each region.

The 2025 NFL season has intensified with Week 5 bringing a thrilling Sunday lineup on October 5. With bye weeks sidelining the Falcons, Bears, Packers, and Steelers. Undefeated teams like the Philadelphia Eagles and Buffalo Bills face tough challenges, while a London matchup and rookie debuts add excitement.

Week 5 of the 2025-26 NFL regular season officially gets underway on Thursday, October 2, with a Thursday Night Football primetime clash featuring the NFC West rival San Francisco 49ers and Los Angeles Rams at SoFi Stadium.

Week 5 of the NFL starts Thursday with an NFC West showdown, followed by aSunday and Monday slate that includes another international game.

CBS and Fox are set to broadcast a combined 13 games on Sunday for NFL Week 3. Here's which ones will air in each region.