RNA viral genomes show hierarchical structural organization. The primary structure encodes proteins, while the secondary and tertiary structures code for essential viral regulatory mechanisms 1.
Domain swapping is the process by which identical monomeric proteins exchange structural elements to generate dimers/oligomers. Although engineered domain swapping is a compelling strategy for protein ...
Human antigen R (HuR) is a key regulator of cellular mRNAs containing adenylate/uridylate–rich elements (AU-rich elements; AREs). These are a major class of cis elements within 3′ untranslated regions ...