Nature

Evaluating the performance of Bayesian and frequentist approaches for longitudinal modeling: application to Alzheimer’s disease

Linear mixed effects (LME) modelling under both frequentist and Bayesian frameworks can be used to study longitudinal trajectories. We studied the performance of both frameworks on different dataset ...
JD Supra

Frequentist or Bayesian? All Roads Lead to Smarter Trials with FDA’s New Bayesian Guidance

Jessica Ritsick, Yifan Wang, Ph.D. Our FDA: Drug & Device Team analyzes the Food and Drug Administration’s new guidance on Bayesian approaches to innovative drug trials, providing greater clarity on ...
Nature

A Bayesian perspective on observers’ inference of group norms

Inferring group norms is crucial for adapting behaviors in novel situations, but its underlying basis and computational account remain unclear. This study manipulated the prevalence of norm-consistent ...
Reason

How To Speed Up the Search for Cures Through a Change in Probability Theory

Marty Makary was appointed commissioner of the Food and Drug Administration (FDA) in 2025. The prominent surgeon, medical researcher, bestselling author, and critic of the medical ...
MedCity News

The FDA’s Bayesian Guidance Could Quietly Reshape Clinical Trial Design

New FDA guidance on the use of Bayesian statistics signals a broader shift in accommodating more flexible clinical trial ...