At 6-5 with a playoff berth within reach, the Carolina Panthers roll into primetime carrying equal parts urgency and belief. Across the field, the 7-4 San Francisco 49ers enter Monday night trying to ...

The San Francisco 49ers are back at Levi’s Stadium in Week 12 of the NFL season with a “Monday Night Football” matchup set against the Carolina Panthers.

The Carolina Panthers face the San Francisco 49ers on Monday, Nov. 24, 2025 at Levi’s Stadium in Santa Clara, California.

The 49ers vs. Browns game will air on CBS and it will stream on Paramount+. Kickoff is scheduled for 1 p.m. ET. Here's ...

Preview the San Francisco 49ers' NFL Week 12 matchup with the Panthers, including live stream, TV channel, odds, and game information.